In Bispecific antibody Preclinical Research, an increasing number of engineered mouse models are used for measuring the roles of CYP enzymes in drug metabolism and toxicity. Human CYP gene(s) have taken the place of mouse Cyp gene(s) in the mouse genome, leading to our understanding of the specific involvement of the given mouse and/or human CYP(s) in a number of aspects of ADME. https://www.creative-biolabs.com/bsab/preclinical-research.htm