CDR assessment
Aug 10, 2019 ·
1m 25s
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Description
In the PreciAbâ„¢ platform, key steps of antibody development are described as follow, Antibody structure construction through combining structure- and homology-based modeling methods Structure optimization by dynamics simulation, rotamer library,...
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In the PreciAbâ„¢ platform, key steps of antibody development are described as follow,
Antibody structure construction through combining structure- and homology-based modeling methods
Structure optimization by dynamics simulation, rotamer library, loop modeling, and etc.
Complementarity-determining region (CDR) identification on the basis of tertiary structure of the antibody
Antibody-antigen complex modeling and interaction analysis
Paratope and epitope identification and key residues analysis
Computer-aided antibody affinity maturation and function modification
Global analysis and optimization of antibody biophysical properties (thermodynamic stability, aggregation propensity, immunogenicity)
https://www.creative-biolabs.com/preciab/preciab-platform.htm
show less
Antibody structure construction through combining structure- and homology-based modeling methods
Structure optimization by dynamics simulation, rotamer library, loop modeling, and etc.
Complementarity-determining region (CDR) identification on the basis of tertiary structure of the antibody
Antibody-antigen complex modeling and interaction analysis
Paratope and epitope identification and key residues analysis
Computer-aided antibody affinity maturation and function modification
Global analysis and optimization of antibody biophysical properties (thermodynamic stability, aggregation propensity, immunogenicity)
https://www.creative-biolabs.com/preciab/preciab-platform.htm
Information
| Author | echo han |
| Organization | echo han |
| Website | - |
| Tags |
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