12 AUG 2019 · CMV is a commonly known virus that can infect almost anyone. Once acquired, the body will retain the virus for life. CMV is usually harmless to organisms so most people are unaware of being infected. Sometimes it results in some long-term consequences in babies, such as hearing loss, visual deficits, or cognitive delays, if a woman catches it during pregnancy so-called congenital CMV. It is also known as herpesvirus type 5, a member of the herpes family that affects a host of individuals across the lifespan. It is often gained during late childhood or early adulthood with rarely symptomatic, except in the compromised immunity. CMV is usual viral pathogens that normally produce a silent sign or asymptomatic symptom in immunocompetent bodies. In all age subjects, this infection has clearly demonstrated a wide and diverse range of disease in immunocompromised hosts. https://www.creative-biolabs.com/drug-discovery/diagnostics/ivd-antibody-development-services-for-cmv.htm
12 AUG 2019 · There are two different types of inflammation: acute and chronic (sometimes called systemic) inflammation. https://www.creative-biolabs.com/drug-discovery/diagnostics/ivd-antibodies-for-inflammatory-disease.htm
While acute inflammation arises after a cut or scrape in the skin, an infected ingrown nail, a sprained ankle, a blow, a sore throat from a cold or flu, or exercise (especially intense training), which starts quickly and generally disappears in a few days. Examples of diseases and conditions with acute inflammation include:
Acute bronchitis
Acute appendicitis
Acute dermatitis
Acute tonsillitis
Acute infective meningitis
Acute sinusitis
Chronic inflammation is long-term that can last for months or years as a result of failure to eliminate the cause and minor, repeated exposure to the agent, an autoimmune response to a self-antigen, or a chronic irritant of low intensity that persists. It occurs in conditions including:
Osteoarthritis
Chronic sinusitis
Chronic active hepatitis
Inflammatory bowel disease
Chronic peptic ulcer
Chronic periodontitis
Tuberculosis
Lupus
Rheumatoid arthritis
Allergies
Asthma
Ulcerative colitis and Crohn's disease
Habitual or environmental factors, such as excess weight, poor diet, lack of exercise, stress, smoking, pollution, poor oral health, excessive alcohol consumption, minor food allergies, a sedentary lifestyle and more can contribute to chronic inflammation.
12 AUG 2019 · Warning signs of pancreatic cancer include pain, weight loss, fatigue, and increased abdominal fluid. Patients complaining about these symptoms often get an evaluation including a physical examination, blood tests, X-rays, and an ultrasound. Computed tomography (CT scan) and endoscopic ultrasound (EUS) are used both to confirm the diagnosis and to help determine the resectability of the tumor. Magnetic resonance imaging (MRI) and positron emission tomography may also be used. If a pancreatic mass is observed, that raises the suspicion of pancreatic cancer and then a biopsy is performed to yield a diagnosis. Pancreatic Cancer marker plays crucial in the diagnosis process. https://www.creative-biolabs.com/drug-discovery/diagnostics/biomarkers-and-antibodies-development-for-pancreatic-cancer.htm
12 AUG 2019 · Diagnosing an autoimmune disease involves identifying the antibodies your body is producing:
Autoantibody tests: any of several tests that look for specific antibodies to your own tissues.
Antinuclear antibody tests: a type of autoantibody test that looks for antinuclear antibodies, which attack the nuclei of cells in your body.
Complete blood count: measures the numbers of red and white cells in your blood; when your immune system is actively fighting something, these numbers will vary from the normal.
C-reactive protein (CRP): elevated CRP is an indication of inflammation throughout your body erythrocyte sedimentation rate: this test indirectly measures how much inflammation is in your body.
https://www.creative-biolabs.com/drug-discovery/diagnostics/autoimmune.htm
12 AUG 2019 · In Vitro Diagnostics (IVD) are tests used to detect and in diagnosis of disease, infections or other medical conditions, including a determination of the state of health, in order to cure, mitigate, treat, or prevent disease or its sequelae. They’re intended for use in the collection, preparation, and examination of specimens taken from the human body.
Common uses for in vitro diagnostics including but not limited to disease screening, infections detecting, therapeutic monitoring, ensuring blood is safe to be used in transfusions, and recognizing of allergies and the measurement of hormones and other biological markers in body specimen. Thus the antibody discovery is quite crucial. https://www.creative-biolabs.com/drug-discovery/diagnostics/
12 AUG 2019 · Tumors can be benign or malignant. Tumors that stay in one spot and demonstrate limited growth are generally considered to be benign. Malignant cells are much “nimbler” than non-malignant ones. Malignant cells can pass more easily through smaller gaps, as well as applying a much greater force on their environment compared to other cells. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. Tumors can grow and interfere with the digestive, nervous, and circulatory system, and they can release hormones that alter body function. https://www.creative-biolabs.com/drug-discovery/diagnostics/cancer.htm
12 AUG 2019 · Composed of two lobes connected by an isthmus, the thyroid gland is an endocrine gland in the neck. It is located at the front of the neck. The main function of thyroid gland is to secrete thyroid hormones, which primarily influence the metabolic mechanism and protein synthesis. Thyroid cancer is cancer that develops from the tissues of the thyroid gland. It is a disease that involves the abnormality of cell growth. Potentially, they have the ability to spread to other parts of the body. Symptoms can include swelling or a lump in the neck. Tumors may originate from and spread into the thyroid and this case is not classified as thyroid cancer. https://www.creative-biolabs.com/drug-discovery/diagnostics/biomarkers-and-antibodies-development-for-thyroid-cancer.htm
12 AUG 2019 · Cancer marker
Cancer is a class of diseases characterized by out-of-control cell growth. In all types of cancer, some of the body's cells begin to divide without stopping and spread into surrounding tissues. Normally, cells in the body follow an orderly path of growth, division, and death. Programmed cell death is called apoptosis, and when this process breaks down, cancer begins to form. Unlike regular cells, cancer cells do not experience programmatic death and instead continue to grow and divide. These extra cells can form a mass called a tumor. https://www.creative-biolabs.com/drug-discovery/diagnostics/cancer.htm
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